I know someone mentioned the ruger LC9 but if you are going for a ruger gun I would go for their Ruger LCR which is a 5 shot revolver that comes in either .357 or .380. It is nice because it has no external spur and the grip extends up far enough that it cushions some of the recoil on your hand. The other nice piece is that it has a 7 lb trigger pull and it is long so the chance of negligent discharge is lessened.
Semi-automatics I am a fan of the Glock family. The Glock 19 and 26 are two good reliable 9mm pistols. Easy to use and easy to clean. BE ADVISED I don't recommend carrying these with a round in the chamber. There is no safety and it has a very easy trigger pull (5 lbs I believe). So there is a chance you could have a negligent discharge if you grab it in a rush.

Ruger LCR

Glock 26

Glock 19
I personally carry a Glock 19 it fits me well. I have a special leather vest I ordered that has built in holsters inside the vest on either side.
Also training, training, training and some more training. Take a conceal carry class. Take a shooting class. Go on your own time to a local range and practice off. Not just target shoot but drawing from a conceal carry holster. Make sure you can draw and by ready to go quickly and smoothly.
www.parkerholster.com has some very good in the waistband conceal carry holsters.
Lastly, remember the LAST thing you want to have to do is shoot someone. Choose all other options before firing. Make sure that if you shoot it is because your life or the life of someone nearby is in imminent danger.
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